国际眼科纵览 ›› 2022, Vol. 46 ›› Issue (5): 443-448.doi: 10.3760/ cma.j.issn.1673-5803.2022.05.011

• 综述 • 上一篇    下一篇

先天性瞳孔残膜的研究进展

周玲琳1 万修华2   

  1. 1浙江省衢州市人民医院眼科中心 324000;2首都医科大学附属北京同仁医院 北京同仁眼科中心 眼科学与视觉科学北京市重点实验室 100730
  • 收稿日期:2021-11-04 出版日期:2022-10-22 发布日期:2022-11-04
  • 通讯作者: 万修华,Email: xiuhuawan@163.com E-mail:xiuhuawan@163.com
  • 基金资助:
    北京市医院管理中心临床医学发展专项经费(XMLX202133);国家自然科学基金(82171037)

Research progress on persistent pupillary membrane

Zhou Linglin1, Wan Xiuhua2   

  1. 1 Department of Ophthalmology, People’s Hospital of Quzhou, Zhejiang 324000, China; 2 Beijing Tongren Eye Center, Beijing Key Laboratory of Ophthalmology and Visual Sciences, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China
  • Received:2021-11-04 Online:2022-10-22 Published:2022-11-04
  • Contact: Wan Xiuhua, Email: xiuhuawan@163.com E-mail:xiuhuawan@163.com
  • Supported by:
    Beijing Hospitals Authority Clinical Medicine Development Special Funding(XMLX202133); National Natural Science Foundation of China(82171037)

摘要: 现有研究认为先天性瞳孔残膜发生可能由于巨噬细胞吞噬功能障碍及成纤维母细胞持久的合成活性所致,但也有病例报告认为与母亲在孕期感染性因素相关,其临床形态有较大差异性,对视力的影响也不同。目前对于其治疗,主要根据残膜的大小和对视力有无影响而定,治疗方法包括药物、激光及手术。(国际眼科纵览,2022, 46:443-448)

关键词: 先天性瞳孔残膜

Abstract: Existing studies believe that occurrence of persistent pupillary membrane may be caused by macrophage phagocytosis dysfunction and persistent synthetic activity of fibroblasts, but there are also case reports considering which related to maternal infectious factors during pregnancy. Its clinical morphology is quite different, and its impact on vision is also different. At present, its treatment is mainly based on the size of the residual membrane and whether it affects vision. The treatment methods mainly include drugs, lasers and surgery. (Int Rev Ophthalmol, 2022, 46: 443-448)

Key words: persistent pupillary membrane