国际眼科纵览

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功能性近红外光谱技术在眼科的应用

柴永馨毕爱玲2,3  温莹2,3   毕宏生2,3   

  1. 1山东中医药大学,济南 250012;2 山东中医药大学附属眼科医院,济南 250002;3 山东省中西医结合眼病防治重点实验室 山东省高校中西医结合眼病防治技术(强化)重点实验室 山东中医药大学眼科研究所,济南 250002
  • 收稿日期:2020-01-13 出版日期:2020-08-22 发布日期:2020-09-01
  • 通讯作者: 毕宏生,Email:hongshengbi1@163.com E-mail:hongshengbi1@163.com
  • 基金资助:
    国家重点研发计划(2019YFC1710204)

Application of functional near-infrared spectroscopy in ophthalmology

Chai Yongxin1, Bi Ailing 2,3, Wen Ying 2,3, Bi Hongsheng 2,3   

  1. 1 Shandong University of Traditional Chinese Medicine, Jinan 250012, China; 2 The Affiliated Eye Hospital of Shandong University of Traditional Chinese Medicine,Jinan 250002, China; 3 Shandong Provincial Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Therapy of Ocular Diseases, Shandong Provincial Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Therapy of Ocular Diseases in Universities, Eye Institute of Shandong University of Traditional Chinese Medicine, Jinan 250002, China
  • Received:2020-01-13 Online:2020-08-22 Published:2020-09-01
  • Contact: Bi Hongsheng, Email: hongshengbi1@163.com E-mail:hongshengbi1@163.com
  • Supported by:
    National Key Research & Development (2019YFC1710204)

摘要: 功能性近红外光谱技术(functional near-infrared spectroscopy,fNIRS)是近几年新兴起的脑功能成像技术,适合在受试者接受刺激任务时同步检测大脑皮层的的血流动力学变化。眼科临床中常见的视觉障碍症状常伴有视皮层的功能异常,fNIRS可以在视觉任务或治疗期间同步检测视皮层的血流动力学反应,为弱视、青光眼、视神经炎、糖尿病视网膜病变等眼科疾病的诊断和疗效评估提供脑参数。

Abstract: Functional near-infrared spectroscopy (fNIRS) is a new brain functional imaging technique developed in recent years, which is suitable for simultaneous detection of hemodynamic changes in the cerebral cortex when subjects are stimulated. Visual disorders commonly seen in ophthalmic clinic are often accompanied by functional abnormalities in the visual cortex. FNIRS can simultaneously detect the hemodynamic responses in the visual cortex during visual tasks or treatment, providing brain parameters for the diagnosis and efficacy evaluation of eye diseases, such as amblyopia, glaucoma, optic neuritis, diabetic retionpathy, etc.