羊膜匀浆液生物学特性研究进展

doi:10.3760/cma.j.issn.1673-5803.2021.02.008

国际眼科纵览 ›› 2021, Vol. 45 ›› Issue (2): 130-134.doi: 10.3760/cma.j.issn.1673-5803.2021.02.008

羊膜匀浆液生物学特性研究进展

胡淑娴张文佳胡竹林

1 昆明医科大学 650504；2 云南大学附属医院云南省第二人民医院云南省眼科研究所云南省眼科疾病预防防治重点实验室，昆明 650021

收稿日期:2020-06-19 出版日期:2021-04-22 发布日期:2021-04-28
通讯作者: 胡竹林，Email：hu-zhulin@163.com
基金资助:
云南省科技厅昆明医科大学应用基础研究联合专项（202001AY070001-255）；2018年云南省卫生科技计划项目（2018NS0012）

Advances in biological characteristics of amniotic membrane extraction

Hu Shuxian1,2, Zhang Wenjia2, Hu Zhulin2

1 Kunming Medical University 650504; 2 Yunnan Eye Institute, Key Laboratory of Yunnan Province for the Prevention and Treatment of Ophthalmology, Yunnan Provincial Second People's Hospital, Affiliated Hospital of Yunnan University, Kunming 650021, China

Received:2020-06-19 Online:2021-04-22 Published:2021-04-28
Contact: Hu Zhulin, Email: hu-zhulin@163.com
Supported by:
Joint Special Project of Applied Basic Reasearch of Kunming Medical University, Department of Science and Technology of Yunnan Province（202001AY070001-255）; Health Science and Technology Program of Yunnan Province in 2018 (2018NS0012)

摘要/Abstract

摘要： 羊膜作为生物膜其保存成本较高，无法持续地对创面输送细胞因子等。羊膜相关制品保留羊膜的一定特性，弥补其不足，为羊膜制品在临床上的应用拓宽了道路。羊膜相关制品的基础为羊膜匀浆。本文将羊膜匀浆液生物学特性（低免疫原性、抗免疫反应、促进伤口愈合、抗眼部新生血管形成、抑制瘢痕形成、抗菌和抑制癌细胞生长等）的研究进展做一综述。（国际眼科纵览，2021, 45：130-134）

关键词: 羊膜, 羊膜匀浆液, 生物特性

Abstract: As a biofilm, amniotic membrane has been used in the medical field for a long time. However, it has disadvantages such as high preservation cost and inability to continuously deliver cytokines to the wound surface. With the research on the active components of amnion, amnion-related products have come out, which retain certain characteristics of amnion, make up for the deficiency of amnion, and broaden the way for the clinical application of amnion products. The basis of amniotic membrane related products is amniotic membrane homogenate. Serum biological characteristics (low immunogenicity and immune response, promote wound healing, anti angiogenesis formation, inhibit scar formation, antibacterial and antimicrobial cancer cell growth, etc.) of amniotic membrane homogenate were reviewed in this paper.(Int Rev Ophthalmol, 2021, 45: 130-134)

Key words: amniotic membrane, amniotic membrane extract, biological characteristics

胡淑娴张文佳胡竹林. 羊膜匀浆液生物学特性研究进展[J]. 国际眼科纵览, 2021, 45(2): 130-134.

Hu Shuxian, Zhang Wenjia, Hu Zhulin. Advances in biological characteristics of amniotic membrane extraction[J]. International Review of Ophthalmology, 2021, 45(2): 130-134.

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[2]	李楠钰，张文佳，胡竹林. 羊膜的制备和保存[J]. 国际眼科纵览, 2019, 43(3): 162-165.
[3]	李楠钰张文佳胡竹林. 羊膜在眼表疾病治疗的研究进展[J]. 国际眼科纵览, 2019, 43(2): 94-99.
[4]	谭叶辉廖武. 复发性翼状胬肉的治疗现状与进展[J]. 国际眼科纵览, 2017, 41(2): 115-121.

羊膜匀浆液生物学特性研究进展

Advances in biological characteristics of amniotic membrane extraction

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