国际眼科纵览 ›› 2024, Vol. 48 ›› Issue (4): 278-283.doi: 10.3760/cma.j.issn.1673-5803.2024.04.007

• 综述 • 上一篇    下一篇

幽门螺旋杆菌感染与眼病的相关性

苗慧1  杨一佺2  吕爱国1  范肃洁1   

  1. 1邯郸市眼科医院(邯郸市第三医院),河北邯郸 056001; 2首都医科大学附属北京同仁医院 北京同仁眼科中心 眼科学与视觉科学北京市重点实验室,北京 100730

  • 收稿日期:2024-04-11 出版日期:2024-08-22 发布日期:2024-08-08
  • 通讯作者: 范肃洁,Email:fansujie3@163.com
  • 基金资助:
    2022年河北省医学适用技术跟踪项目(GZ2022094)

The correlation between helicobacter pylori infection and eye diseases

Miao Hui1, Yang Yiquan2, Lv Aiguo1, Fan Sujie1   

  1. 1 Handan City Eye Hospital (The Third Hospital of Handan), Handan Hebei 056001, China; 2 Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University; Beijing Key Laboratory of Ophthalmology and Visual Science, Beijing 100730, China

  • Received:2024-04-11 Online:2024-08-22 Published:2024-08-08
  • Contact: Fan Sujie, Email: fansujie3@163.com
  • Supported by:
    2022 Hebei Province Medical Applicable Technology Tracking Program(GZ2022094)

摘要: 幽门螺旋杆菌是一种具有鞭毛的革兰阴性菌,除造成胃肠道感染外,与其他系统疾病也有一定的关联,如自身免疫性疾病、心脑血管系统疾病、内分泌系统疾病变等。近年研究发现幽门螺杆菌感染对一些眼病也有不良影响,如睑缘炎、青光眼、中心性浆液性脉络膜视网膜病变等。幽门螺旋杆菌可通过刺激炎性介质的释放、刺激产生抗体和效应T细胞、分子模拟等机制参与相关眼病的发生和发展。根除幽门螺旋杆菌或许有助于治疗以上眼病。 (国际眼科纵览,2024, 48:278-283)


关键词: 幽门螺旋杆菌, 眼病

Abstract: Helicobacter pylori is a gram-negative bacterium with flagella. In addition to causing gastrointestinal infections, it is also associated with other systemic diseases such as autoimmune diseases, cardiovascular and cerebrovascular diseases, endocrine system diseases, etc. In recent years, increasing studies have found that helicobacter pylori infection also has adverse effects on some eye diseases, such as blepharitis, glaucoma, and central serous chorioretinopathy. Helicobacter pylori can participate in the occurrence and development of the related eye diseases through mechanisms such as stimulating the release of inflammatory mediators, the production of antibodies and effector T cells, and molecular mimicry. Eradicating helicobacter pylori may help treat the aforementioned eye diseases.(Int Rev Ophthalmol, 2024, 48:  278-283)


Key words: helicobacter pylori, eye diseases