国际眼科纵览 ›› 2024, Vol. 48 ›› Issue (4): 310-315.doi: 10.3760/cma.j.issn.1673-5803.2024.04.012

• 综述 • 上一篇    下一篇

抑郁与干眼的关系

马玥妮  杨瑞波   

  1. 天津医科大学眼科医院 天津医科大学眼视光学院 天津医科大学眼科研究所 国家眼耳鼻喉疾病临床医学研究中心天津市分中心 天津市视网膜功能与疾病重点实验室,天津 300384
  • 收稿日期:2024-04-24 出版日期:2024-08-22 发布日期:2024-08-08
  • 通讯作者: 杨瑞波,Email:yangruibo771@163.com
  • 基金资助:
    天津市医学重点学科(专科)建设项目(TJYXZDXK-037A);天津市临床重点学科(专科)建设项目(TJLCZDXKM002)

Relationship between depression and dry eye

Ma Yueni, Yang Ruibo   

  1. Tianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Branch of National Clinical Research Center for Ocular Disease, Eye Institute and School of Optometry, Tianjin Medical University Eye Hospital, Tianjin 300384, China

  • Received:2024-04-24 Online:2024-08-22 Published:2024-08-08
  • Contact: Yang Ruibo, Email: yangruibo771@163.com
  • Supported by:
    Tianjin Key Medical Discipline(Specialty) Construction Project (TJYXZDXK-037A);Tianjin Clinical Key Discipline Project (TJLCZDXKM002)

摘要: 抑郁与干眼均为危害患者生理及心理健康的重要公共卫生问题,二者互为因果,形成恶性循环。炎症、自主神经功能紊乱等为抑郁和干眼的共病机制。抑郁相关性干眼属于抑郁患者伴发的一种慢性疼痛,而干眼属于抑郁患者的一项躯体化症状。抗抑郁药物可加剧甚至诱发干眼。干眼带来的一系列眼表刺激症状也会引起患者的不良情绪。 (国际眼科纵览,2024, 48:310-315)


关键词: 抑郁, 干眼

Abstract: Depression and dry eye are both major social and public health problems that endanger the physiological and psychological health of patients, and they are mutually causative, forming a vicious circle. Inflammation and autonomic dysfunction may be the co-morbid mechanisms of depression and dry eye. Depression-associated dry eye is a chronic pain associated with depression, or dry eye itself is a somatised symptom in depressed patients. Antidepressants can exacerbate or even induce dry eyes. A series of ocular surface irritation symptoms brought about by dry eyes can also cause bad mood in patients. (Int Rev Ophthalmol, 2024, 48:   310-315)


Key words: depression, dry eye