国际眼科纵览

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筛板前组织的OCT影像检测及其与眼病的关系

张琪 王亚星 李建军 徐亮   

  1. 100005 首都医科大学附属北京同仁医院 北京市眼科研究所 北京同仁眼科中心 眼科学与视觉科学北京市重点实验室
  • 收稿日期:2017-01-04 出版日期:2017-02-22 发布日期:2017-02-20
  • 通讯作者: 徐亮,Email: xlbio1@163.com

Optical coherence tomograph of prelaminar tissue and its relationship with oculopathy

ZHANG Qi, WANG Ya-xing, LI Jian-jun, XU Liang   

  1. Beijing Instisute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Key Lab. of Ophthalmology and Visual Science, Beijing 100005, China
  • Received:2017-01-04 Online:2017-02-22 Published:2017-02-20
  • Contact: XU Liang, Email: xlbio1@163.com

摘要:

筛板前组织是位于视乳头筛板前区的结构性组织,其与筛板组织一样均为青光眼性视神经损害中不可缺少的部分。筛板前组织厚度可通过OCT观察,其在眼压增高及缺血时会变薄,在青光眼术后眼压降低时会增厚。所以探索筛板前组织的变化可能有利于揭示青光眼的发病机制,并为青光眼随诊提供临床生物学指标。此外,也有些研究发现筛板前组织变化与缺血性视神经病变、糖尿病视神经病变、视网膜色素变性相关。(国际眼科纵览, 2017,  41:  8-13)

Abstract:

The prelaminar tissue locates anterior to the lamina cribrosa. The prelaminar tissue and lamina cribrosa tissue are both indispensable parts in the process of glaucomatous optic neuropathy. With the development of optical coherence tomography(OCT), these tissues become observable in vivo. The thickness of prelaminar tissue becomes thinner during intraocular pressure (IOP) elevation and ischemia, and thicker after IOP reduction caused by glaucoma surgery. Explorement of the changes of the prelaminar tissue might be helpful to understand the pathogenesis of these diseases. Prelaminar tissue thickness can also provide clinical biomarker for monitoring glaucoma during patient follow-up. In addition, some investigators have found that the prelaminar tissue is related to ischemic optic neuropathy, diabetic optic neuropathy and retinitis pigmentosa.  (Int Rev Ophthalmol,  2017,  41:   8-13)