Abstract: Presbyopia is the physical defect which every human being will be affected with as the accommodation decreases with age and therefore working at close range may be difficult. The well accepted reason for presbyopia is the agerelated hardening of crystalline lens, decreased flexibility and deformability as well as a loss of the accommodative power. As a possible treatment option, femtosecond laser is a promising tool to make microcuts inside the lens to creat gliding planes at desired depth and shape via the effect of laserinduced optical breakdown, hence the flexibility and deformability of the tissue is supposed to be reestablished and the potential adjustment power may be reconstructed dynamically as a result. Several reasearches have verified the therapeutic effect, effectiveness and safety of this innovative technology. Still, certain problems remain untackled. The purpose of this review is to outline the theoretical basis, experimental study, effect and the problems faced to discuss this evolving technology in presbyopia treatment.  (Int Rev Ophthalmol, 2012, 36: 73-77)