Abstract:

Dry eye has become an increasingly common ophthalmic disease, and diabetes mellitus is one of its high risk factors. In recent years, people pay much attention to diabetes-related dry eye. The two diseases are both related to the immune system disorders. A large number of studies at home and abroad have proved that plasmacytoid dendritic cells play an important role in the regulation of immune inflammatory response. It can not only connect congenital immunity and adaptived immunity, but also has the ability to innate the immune inflammatory response. While its immune dysfunction will lead to immune disorders, triggering a series of immune inflammatory cascade reaction. Therefore, plasmacytoid dendritic cells may play a prominent role in immune pathogenesis of diabetes-related dry eye.