Abstract: In recent years, optical coherence tomography(OCT) has been used to study retinal nerve fiber layer thickness(RNFLT) in patients with congenital cataract deprivation amblyopia. The studies showed that RNFLT became thinner in the short term after cataract surgery. However, in the long-term, the RNFLT was thicker than the control group. Therefore, it is believed that the RNFLT in eyes with congenital cataract deprivation amblyopia may be abnormally thick.(Int Rev Ophthalmol, 2019, 43: 199-203)