国际眼科纵览

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先天性无虹膜症并发白内障的研究进展

王进达 万修华   

  1. 100005 首都医科大学附属北京同仁医院 北京同仁眼科中心 北京市眼科研究所 眼科学与视觉科学北京市重点实验室
  • 收稿日期:2015-08-18 出版日期:2018-02-22 发布日期:2018-03-08
  • 通讯作者: 万修华,Email:xiuhuawan@163.com E-mail:xiuhuawan@163.com
  • 基金资助:

    北京市科技新星项目(H020821380190;Z131102000413025);国务院妇女儿童工作委员会课题(2014108);国家自然科学基金面上项目(30471861;81470635);北京市眼科研究所引领计划(201515)

Progress of study on congenital aniridia with cataract

WANG Jin-da, WAN Xiu-hua   

  1. Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Key Laboratory of Ophthalmology and Visual Sciences, Beijing 100005, China
  • Received:2015-08-18 Online:2018-02-22 Published:2018-03-08
  • Contact: WAN Xiu-hua, Email:xiuhuawan@163.com E-mail:xiuhuawan@163.com
  • Supported by:

    Beijing New Star of Science and Technology (H020821380190; Z131102000413025); Fund of Work Committee for Women and Children of China State Department (2014108);  National Natural Science Fund of China (30471861; 81470635); The Leading Project of Beijing Institute of Ophthalmology (201515)

摘要:

先天性无虹膜症是一种少见的眼部遗传病,合并白内障几率很高,通常需要手术治疗,但该类白内障手术难度大、风险高、术后视力提高有限。虹膜型人工晶状体的植入虽然可以改善畏光症状,但存在继发青光眼、角膜内皮失代偿等严重并发症,应慎重应用。由于患者同时合并其他先天异常,白内障术后密切随诊,及时处理相应眼部改变对预后非常重要。

Abstract:

Congenital aniridia is a rare genetic eye disease. There is a high cataract prevalence in these patients and the cataract surgery usually required. But the kind of cataract surgery is difficult and usually in high risk. The postoperative visual acuity improved limited. The symptoms of photophobia can be decreased when iris-type IOL was implanted, but there are serious complications of secondary glaucoma, corneal endothelial decompensation, etc. So the iris-type IOL should be carefully applied. Because patients are also associated with other congenital anomalies, it is very important to the prognosis that the patients is closely followed up and do something for ocular changes accordingly in time after cataract surgery.