Abstract: Transepithelial photorefractive keratectomy (Trans-PRK) is a new type of corneal surface surgery. It has the characteristics of more accurate cutting, no negative pressure suction and no incision. The change of the cutting mode reduces the previous surface surgery Postoperative pain, improves epithelial healing delays and other issues. At present, its safety and efficacy have been verified, but the recovery of corneal nerve fibers, corneal biomechanical changes and postoperative related complications still need to be further studied and improved. (Int Rev Ophthalmol, 2020, 44： 112-116)