Abstract:

Cogan′s syndrome (CS) is a rare disease,characterized by nonsyphilitic ocular keratitis and vestibuloauditory dysfunction.  The cause of the disease is unclear. It may be an autoimmune disease. The inicidence of the disease is mostly young people. The main manifestation are nonsyphilitic ocular keratitis and vestibulo auditory dysfunction. The CS is divided into typical and atypical. It needs to differentiate with granulomatosis with polyangiitis, rheumatoid arthritis, systemic lupus erythematosus. The treatment is mainly with glucocorticoids and immunosuppressive agents.(Int Rev Ophthalmol,  2017,  41:   328-331)