Abstract: Helicobacter pylori is a gram-negative bacterium with flagella. In addition to causing gastrointestinal infections, it is also associated with other systemic diseases such as autoimmune diseases, cardiovascular and cerebrovascular diseases, endocrine system diseases, etc. In recent years, increasing studies have found that helicobacter pylori infection also has adverse effects on some eye diseases, such as blepharitis, glaucoma, and central serous chorioretinopathy. Helicobacter pylori can participate in the occurrence and development of the related eye diseases through mechanisms such as stimulating the release of inflammatory mediators, the production of antibodies and effector T cells, and molecular mimicry. Eradicating helicobacter pylori may help treat the aforementioned eye diseases.(Int Rev Ophthalmol, 2024, 48:  278-283)

Key words: helicobacter pylori, eye diseases