International Review of Ophthalmology

    Next Articles

Axonal regeneration mechanisms after central nervous system injury

WU Ya-li, YU Min-bin   

  1. State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, China
  • Received:2018-06-23 Online:2018-12-22 Published:2018-12-22
  • Contact: YU Min-bin, Email: yuminbin@mail.sysu.edu.cn
  • Supported by:

    Guangdong Provincial Natural Science Foundation（2015A030312016）

Abstract:

Decreased axonal regeneration after central nervous system injury in adult mammals and inhibition of the mature axon by extracellular environment together lead to axonal regeneration disorders. At present, the promotion of neuronal axon repair and regeneration is mainly carried out by reducing the production of myelin inhibitory factor, reducing the glial scar reaction combined with stem cell transplantation, neurotrophic factors, and rehabilitation training. (Int Rev Ophthalmol, 2018, 42:   361-366)