Abstract: Contact lens（CL）is a common method for refraction correction, which not only can correct vision but also being used in a wide range of areas, such as biosensing and drug release. As a biosensor, contact lens can be used to continuously monitor intraocular pressure, monitor glucose in tear film and diagnose diseases. As a drug carrier, CL can extend the duration of drug release. Howere, there are still some problems to be solved in the innovative application of contact lenses, such as results validation and the aesthetics tissue. (Int Rev Ophthalmol, 2019, 43: 157-161)