International Review of Ophthalmology

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The protective effect and its potential mechanism of the epigallocatechin gallate in retinal diseases

Xu Jiaowen, Zhu Manhui, Song E   

  1. Department of Ophthalmology, Lixiang Eye Hospital of Soochow University, Suzhou 215000, China
  • Received:2019-06-10 Online:2019-12-22 Published:2019-12-26
  • Contact: SONG E，Email：songe@suda.edu.cn
  • Supported by:

    Jiangsu Distinguished Medical Experts Program (2016); Suzhou Science and Technology Bureau (SYS2018004)

Abstract:

Epgallocatechin gallate (EGCG) is the main active ingredient of polyphenols in green tea, which has beneficial effects on many diseases. It has protective effect on retina through antioxidant, anti-inflammatory, hypoglycemic, neuroprotective, inhibiting apoptosis and angiogenesis. It plays a preventive role in age-related macular degeneration, diabetic retinopathy and other retinal diseases.(Int Rev Ophthalmol, 2019, 43: 390-395)