International Review of Ophthalmology ›› 2021, Vol. 45 ›› Issue (2): 130-134.doi: 10.3760/cma.j.issn.1673-5803.2021.02.008

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Advances in biological characteristics of amniotic membrane extraction

Hu Shuxian1,2, Zhang Wenjia2, Hu Zhulin2   

  1. 1 Kunming Medical University 650504; 2 Yunnan Eye Institute, Key Laboratory of Yunnan Province for the Prevention and Treatment of Ophthalmology, Yunnan Provincial Second People's Hospital, Affiliated Hospital of Yunnan University, Kunming 650021, China
  • Received:2020-06-19 Online:2021-04-22 Published:2021-04-28
  • Contact: Hu Zhulin, Email: hu-zhulin@163.com
  • Supported by:
    Joint Special Project of Applied Basic Reasearch of Kunming Medical University, Department of Science and Technology of Yunnan Province（202001AY070001-255）; Health Science and Technology Program of Yunnan Province in 2018 (2018NS0012)　　

Abstract: As a biofilm, amniotic membrane has been used in the medical field for a long time. However, it has disadvantages such as high preservation cost and inability to continuously deliver cytokines to the wound surface. With the research on the active components of amnion, amnion-related products have come out, which retain certain characteristics of amnion, make up for the deficiency of amnion, and broaden the way for the clinical application of amnion products. The basis of amniotic membrane related products is amniotic membrane homogenate. Serum biological characteristics (low immunogenicity and immune response, promote wound healing, anti angiogenesis formation, inhibit scar formation, antibacterial and antimicrobial cancer cell growth, etc.) of amniotic membrane homogenate were reviewed in this paper.(Int Rev Ophthalmol, 2021, 45: 130-134)


Key words: amniotic membrane, amniotic membrane extract, biological characteristics