Abstract: Halo and other visual problems can worsen patient’s visual quality after the implantation of multifocus intraocular lens (mIOL), which is related to the neural adaptation of the brain. Studies have found that there are individual differences in neural adaptation, and younger patients are more prone to have neural adaptation. Neural adaptation is related to retinal image processing and the corresponding cerebral cortex activity. To achieve stable neural adaptation needs at least 6 months. Video games, computer cognitive training or computer visual training can improve the neural adaptation of patients after multifocus IOL implantation.  (Int Rev Ophthalmol, 2022, 46:  289-296)

Key words: multifocal intraocular lens, neural adaptation