Ophthalmology in China

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The correlations between choroidal thickness and degree of myopia in Chinese 

SUN Qian, PENG Xiao-yan, ZHOU Yue-hua, SONG Xiu-mei, ZHENG Yan, LIU Qian, ZHANG Jing.   

  1. Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University; Beijing Key Lab. of Ophthalmology & Visual Sciences, Beijing 100005, China
  • Received:2017-01-19 Online:2017-07-25 Published:2017-07-24
  • Contact: PENG Xiao-yan, Email: pengxiaoyan133@sina.com


 Objective To evaluate the correlations between choroidal thickness and degree of myopia in Chinese. Design Retrospective case series. Participants A total of 470 eyes (248 consecutive patients) were observed at the Tongren Eye Center.  Method Choroidal and retinal biometry was measured using RTVue OCT[DL-Medsci1]. Choroidal thickness measurements were obtained manually at the point of fovea, and at 500, 1000, and 2000 μm apart from the fovea in the nasal, temporal, superior, and inferior directions. The mean retinal thickness was calculated by the software of the RTVue OCT. Main Outcome Measures Choroidal thickness, retinal thickness and axial length.  Results There were no differences in the choroidal thickness at the fovea and each points between mild and moderate myopia (P>0.05), while there were differences between mild and high myopia, mild and super-high myopia, moderate and high myopia, moderate and super-high myopia, and high and super-high myopia (all P<0.001). There were no differences in the retinal thickness at the fovea (all P>0.05). Age (P=0.019) and macular choroidal thickness (P<0.01) were independently related to best corrected visual acuity (P<0.05). Both macular choroidal thickness and subfovea choroidal thickness was significantly different between the two groups of patients with and without normal best-corrected visual acuity. Conclusions Macular choroidal thickness could be associated with the development of myopia. The macular choroidal thickness could be a good indicator of myopic maculopathy. (Ophthalmol CHN, 2017, 26: 256-261)

Key words: myopia, choroidal thickness