Abstract:

Objective To study the effect of preoperative glucocorticoid application on anatomical reduction of rhegmatogenous retinal detachment associated with choroidal detachment (RRDCD) after vitrectomy. Design  Retrospective case series. Participants 155 cases (155 eyes) diagnosed as RRDCD were enrolled. Methods The patients were divided into 4 groups according to preoperative glucocorticoid use: 43 eyes without glucocorticoid (group A); 42 eyes with oral glucocorticoid (group B); 32 eyes with glucocorticoid peribulbar injection (group C); and 38 eyes with triamcinolone acetonide intravitreal injection (group D). All patients underwent vitrectomy for the first time. The retinal anatomic reattachment was observed 6 months after operation. Main Outcome Measures The retinal reattachment after vitrectomy. Results After vitrectomy, retinal reattached in 27 eyes (62.79%) in group A, 37 eyes (88.10%) in group B, 29 eyes (90.63%) in group C, and 34 eyes (89.47%) in group D. There were significant differences between group A and the other three groups (all P<0.05), while no significant difference was found among B, C and D groups (all P>0.05). Conclusion For patients with RRDCD, preoperative corticosteroids can improve the rate of retinal reattachment. No significant difference was found in successful rate of retinal reattachment after vitrectomy, no matter oral administration, peribulbar injection or intravitreal injection of different glucocorticoid was applicate. Suitable modes of administration and glucocorticoids types could be chosen for patients according to the systemic and ocular conditions.

Key words: retinal detachment, choroid detachment, glucocorticoids, vitrectomy