Abstract:  Objective To evaluate the effectiveness of Alvarez zoom lens-based biofeedback training glasses with progressive accommodation function as a tool for improving accommodative lag and accommodative amplitude in children and adolescents. Design Randomized controlled trial. Participants 32 adolescents aged between 8 and 16 years. Methods Participants were randomly divided into two groups. The training group wore biofeedback training glasses with accommodative function during daily close-up activities, training twice a day for 30 minutes each time. The control group maintained their daily close-up vision habits unchanged. Routine and accommodative function tests were performed before and 4 weeks after training. Accommodative function tests included accommodation response, AC/A, negative relative accommodation, positive relative accommodation, accommodative amplitude, and accommodative facility. Main Outcome Measures Accommodative amplitude and accommodative facility. Results A total of 32 participants were enrolled, including 9 females and 7 males in the training group with a mean age of 9.3±2.8 years and a diopter of -1.36±1.27 D, and 8 females and 8 males in the control group with a mean age of 10.3±2.6 years and a diopter of -0.95±2.18 D. Before training, there was no significant difference in accommodative function test results between the two groups. After four weeks of training, the training group showed significant improvements with an increase in accommodative amplitude by 4.95 D (95% CI: 2.60 to 7.30 D), an increase in accommodative facility by 2.6 cycles per minute (95% CI: 0.8 to 4.4 cycles per minute), a decrease in accommodative lag by 0.66D (95% CI: -1.20 to 0.12 D), and an increase in negative relative accommodation by 0.36 D (95% CI: 0.04 to 0.71 D). No significant changes were observed in the control group. At the end of the trial, the training group had significantly higher accommodative amplitude (t=3.147, P=0.004) and accommodative facility (t=2.527, P=0.017) compared to the control group. Conclusion Alvarez zoom lens-based biofeedback training glasses with progressive accommodation function can improve accommodative amplitude and accommodative response in adolescents. Further studies are warranted to evaluate its impact on the progression of myopia in adolescents. (Ophthalmol CHN, 2024, 33: 356-361)

Key words: adolescents myopia, accommodative function, Alvarez zoom lens