Ophthalmology in China ›› 2022, Vol. 31 ›› Issue (2): 109-114.doi: 10.13281/j.cnki.issn.1004-4469.2022.02.006

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Efficacy and safety of gonioscopy assisted transluminal trabeculotomy (GATT) for primary childhood glaucoma

Gao Chuanwen1, Zhang Weijia2, Di Haohao1, Qin Shujuan1, Jin Jing1, Zhao Zhiling1, Jia Fei1, Wang Huaizhou2   

  1. 1 Department of Ophthalmology, Zhengzhou Second Hospital, Zhengzhou Hospital, Jinan University, Zhengzhou 450000, China; 2 Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Key Laboratory of Ophthalmology and Visual Science, Beijing 100730, China

  • Received:2021-12-08 Online:2022-03-25 Published:2022-03-25
  • Contact: Wang Huaizhou, Email: trhz_wang@163.com
  • Supported by:
    Henan Province Medical Science and Technology Research Program Joint Construction Project（LHGJ20191012）

Abstract:  Objective To evaluate the efficacy and safety of gonioscopy assisted transluminal trabeculotomy (GATT) for the surgical management of primary childhood glaucoma. Design Retrospective case series. Participants Consecutive 8 primary congenital glaucoma (PCG) patients (9 eyes) with mean age 2.4±1.5 years old and 15 juvenile open angle glaucome(JOAG) patients (20 eyes)  with mean age 19.0±7.2 years old underwent GATT between April 2018 and July 2019 by a single surgeon in Zhengzhou Second Hospital. Methods Medical records of patients were reviewed. Intraocular pressure (IOP) and usage of anti-glaucoma medication were compared between before surgery and last visit after surgery. Surgical success was defined as a postoperative IOP of ≤ 21 mmHg with (qualified success) or without (complete success) the use of anti-glaucoma medication. Mean follow-up time was 27.5±3.7 months (range 24-36 months). Main Outcome Measures IOP, number of anti-glaucoma medications, surgical complications. Results  Post-operative IOP (14.3±3.5 mmHg) and number of anti-glaucoma medication (0, range 0-3) decreased significantly compared with the pre-operative values (30.4±12.2) mmHg (t=7.4, P＜0.001), 3 (range2~5） (z=-4.7, P＜0.001), respectively. The complete success rate was 72.4% and the qualified success rate was 93.1%. Hyphema was seen in all eyes (29/29, 100%), 14/29(48.3%) eyes had IOP spike in early stage after surgery. There was no severe complications occurred in all cases. Conclusion GATT has a medium and long-term effectiveness and is safety in the management of PCG and JOAG. （Ophthalmol CHN, 2022, 31: 109-114）


Key words: gonioscopy assisted transluminal trabeculotomy (GATT), primary congenital glaucoma (PCG), juvenile open angle glaucoma (JOAG)