Abstract:  Objective To assess the clinical effect of Nd∶YAG laser click membrane in the treatment of secondary glaucoma associated with pupillary occlusion. Design Retrospective case series. Participants 15 cases (15 eyes) of secondary glaucoma associated with pupillary occlusion and pupillary membrane from 2008 to 2012 in Third People’s Hospital of Dalian. Method In all patients Nd∶YAG laser was used to click pupil membrane with 0.4-1.0 mJ of single pulse for relieving the occlusion of pupil. All patients were followed up for 6 months. Main Outcome Measures Intraocular pressure (IOP), corneal endothelial count and vision before and after operation. Results  Average pre-operative IOP was (43.2±13.7) mmHg which was significantly different from the last follow-up IOP (15.6±5.2) mmHg(t=8.76, P=0.000). After laser therapy, 1 eye was treated with combined medication therapy, 2 eyes with trabeculectomy. Corneal endothelial cell count at pre-operation was (2272.0±431.8) /mm2, and (2226.9±422.9) /mm2 at post-operation. Pre-operative visual acuity was from hand motion to 0.12, and post-operative visual acuity was from 0.1 to 0.6. There was no significant injury of cornea endothelial cells and lens. Conclusions  Nd∶YAG laser for secondary glaucoma associated with pupillary occlusion and a gap between the lens and pupil is safe and effective. (Ophthalmol CHN, 2014, 23: 260-263)  

Key words: pupillary occlusion, secondary glaucoma, Nd∶YAG laser