Abstract:

Objective To understand the hot spots and breakthrough on ophthalmology by searching and reading articles published in The Journal of American Medical Association（JAMA） from the year 2000 to 2014.  Design Literature search and analysis．Participants Articles on ophthalmology were published from Jan. 2000 to Feb. 2014 in JAMA. Methods In Pubmed database, we chose the database “JAMA” and then selected “MeSH Terms” and inputted “eye” and all its inferior MeSH terms. Further screening was done by reading titles and abstracts of the articles as well as reading the necessary part of the full article. Main Outcome Measures Literature types. Results Among 92 included articles, 26 (28.3%) were original articles，38 (41.3%) were comments, 6 (6.5%) were letters, 10(10.9%) were reviews and 12(13.0%) were case reports． When classified by research content, 30 (32.6%) articles were mainly about etiology and risk factors, 14 (15.2%) were about treatment and 21(22.8%) were about comprehensive evaluation of disease. According to research type of the 26 original articles, 8 articles were cohort study, 6 articles were longitudinal study, 5 articles were cross-sectional study, 3 articles were case-control study, 3 articles were RCTs (including one multicenter randomized controlled trial) and another one paper. In terms of the nationality of authors, American accounted for 58 (63.0%) pieces, Britain and Canadian both accounted for 6 (6.5%) pieces, Chinese accounted for 1 (1.1%) comment, Chinese in Taiwan accounted for 1 (1.1%) case report and others accounted for 20 (21.7%) pieces. As for disease types, the most concerned disease was age related macular degeneration (AMD), accounting for 14 (15.2%) pieces and 6 articles of them were about etiology and risk factors of AMD. Following was about cataract, accounting for 13 (14.1%) pieces and 7 articles were about prognosis of operation. Retinal detachment accounted for 10 (10.9%) pieces while diabetic retinopathy accounted for 9 (9.8%) pieces.  Conclusion The focus of JAMA in ophthalmology was on etiology and treatment of retinal disease like AMD and prognosis of cataract operation. While in methodology, cohort study, longitudinal study and cross-sectional study were most often used. What’s more, it showed obvious local characteristics that most papers were published by American authors. (Ophthalmol CHN， 2016, 25： 418-422)

Key words: The Journal of American Medical Association（JAMA）, eye diseases