国际眼科纵览

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表没食子儿茶素没食子酸酯在视网膜疾病中的作用及其机制

徐交文 朱曼辉 宋鄂   

  1. 苏州大学理想眼科医院眼科 215000
  • 收稿日期:2019-06-10 出版日期:2019-12-22 发布日期:2019-12-26
  • 通讯作者: 宋鄂,Email:songe@suda.edu.cn
  • 基金资助:

    江苏省特聘医学专家人才项目(2016);苏州市科技局课题(SYS2018004)

The protective effect and its potential mechanism of the epigallocatechin gallate in retinal diseases

Xu Jiaowen, Zhu Manhui, Song E   

  1. Department of Ophthalmology, Lixiang Eye Hospital of Soochow University, Suzhou 215000, China
  • Received:2019-06-10 Online:2019-12-22 Published:2019-12-26
  • Contact: SONG E,Email:songe@suda.edu.cn
  • Supported by:

    Jiangsu Distinguished Medical Experts Program (2016); Suzhou Science and Technology Bureau (SYS2018004)

摘要:

表没食子儿茶素没食子酸酯(epigallocatechin gallate,EGCG)是绿茶中多酚类的主要有效成分,可通过抗氧化、抗炎、降糖、神经保护、抑制细胞凋亡和抑制血管生成等多种方式对视网膜起到保护作用。在年龄相关性黄斑变性、糖尿病视网膜病变等视网膜疾病的防治中具有潜在的预防作用。(国际眼科纵览,2019, 43: 390-395)

Abstract:

Epgallocatechin gallate (EGCG) is the main active ingredient of polyphenols in green tea, which has beneficial effects on many diseases. It has protective effect on retina through antioxidant, anti-inflammatory, hypoglycemic, neuroprotective, inhibiting apoptosis and angiogenesis. It plays a preventive role in age-related macular degeneration, diabetic retinopathy and other retinal diseases.(Int Rev Ophthalmol, 2019, 43: 390-395)