Abstract: 【Abstract】Filtering bleb scarring is the main determinant factor leading to the failure of glaucoma filtering surgery. The vascular endothelial growth factor (VEGF) has been proved to be a significant role in the process of angiogenesis, wound healing and scar formation. In recent years, ophthalmologists have applied VEGF inhibitor bevacizumab to glaucoma filtering surgery as an adjunct for inhibiting postoperative scarring, which shows good effect to promote the functioning bleb formation, control the intraocular pressure, thereby improve surgical outcome. This article reviewed the experimental study and clinical application of VEGF inhibitor bevacizumab in glaucoma filtering surgery. (Int Rev Ophthalmol, 2012, 36: 298301)