国际眼科纵览

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豹纹状眼底改变研究进展

延艳妮   魏文斌   

  1. 100730 首都医科大学附属北京同仁医院 北京同仁眼科中心 眼内肿瘤诊治研究北京市重点实验室 眼科学与视觉科学北京市重点实验室
  • 收稿日期:2016-07-13 出版日期:2017-12-22 发布日期:2017-12-21
  • 通讯作者: 魏文斌,Email:weiwenbintr@163.com
  • 基金资助:

    北京市医院管理局“登峰”人才培养计划(DFL20150201);国家自然科学基金(81570891);北京市自然科学基金(7151003);北京市卫生系统高层次卫生技术人才培养计划(2014-2-003);首都卫生发展科研专项项目(首发2016-1-2051)

Research progression on fundus tessellation

YAN Yan-ni, WEI Wen-bin   

  1. Beijing Tongren Eye Center,Beijing Key Laboratory of Intraocular Tumor Diagnosis and Treatment, Beijing Key Laboratory of Ophthalmology & Visual Sciences,  Beijing Tongren Hospital, Capital Medical University, Beijing 100730,China
  • Received:2016-07-13 Online:2017-12-22 Published:2017-12-21
  • Contact: WEI Wen-bin, Email: weiwenbintr@163.com
  • Supported by:

     Beijing Municipal Administration of Hospitals’Ascent Plan (DFL20150201) ; National Natural Science Foundation of China (81570891); Beijing Natural Science Foundation (7151003); Advanced Health Care Professionals Development Project of Beijing Municipal Health Bureau (2014-2-003); The Capital Health Researh and Development of Special(2016-1-2051)

摘要:

豹纹状眼底改变指在除盘周区域外的眼底后极部透见脉络膜大血管。其原因可能为视网膜色素上皮透见性增加、脉络膜毛细血管层萎缩、脉络膜大血管间色素沉积等。豹纹状眼底改变程度与中心凹下脉络膜厚度呈显著负相关,通过观察豹纹状眼底的改变程度可估计中心凹下脉络膜厚度。此外,豹纹状眼底改变与高度近视眼底病变、原发性开角型青光眼、年龄相关性黄斑变性等疾病相关,其为这些疾病的诊断、鉴别诊断及发病机制的探索提供依据。(国际眼科纵览, 2017,  41:   367-371)

Abstract:

Fundus tessellation has been defined as the visibility of large choroidal vessels at the posterior fundus pole outside of the peripapillary region. Factors on the increased visibility of the large choroidal vessels in eyes with a marked fundus tessellation may include an increased transparency of the retinal pigment epithelium, an reduced filling of the choriocapillaris, an increased pigmentation of the intrachoroidal regions between the large horoidal vessels. Thinner subfoveal choroidal thickness is strongly associated with higher degree of fundus tessellation. Observing fundus tessellation is useful for estimating choroidal thickness. Additionally, fundus tessellation is associated with diseases like high myopia, primary open angle glaucoma and age-related macular degeneration. Observing fundus tessellation is useful for diagnosis, differential diagnosis and exploring pathogenesis of these eye diseases. (Int Rev Ophthalmol,  2017,  41:   367-371)