国际眼科纵览

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眼外肌注射肉毒毒素及布比卡因治疗斜视

郭奕钦,艾立坤   

  1. 100730首都医科大学附属北京同仁医院 北京同仁眼科中心 眼科学与视觉科学北京市重点实验室(郭奕钦系在读硕士研究生)
  • 收稿日期:2018-03-31 出版日期:2018-06-22 发布日期:2018-06-28
  • 通讯作者: 艾立坤,Email:likun_ai2406@yahoo.com
  • 基金资助:

    国家自然科学基金(61271151)

Indications for botulinum toxin and bupivacaine injection to extraocular muscle for treating strabismus

GUO Yi-qin, AI Li-kun   

  1. Beijing Tongren Eye Center, Beijing Key Laboratory of Ophthalmology and Visual Sciences,  Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China
  • Received:2018-03-31 Online:2018-06-22 Published:2018-06-28
  • Contact: AI Li-kun, Email: likun_ai2406@yahoo.com
  • Supported by:

    National Natural Science Foundation of China (61271151)

摘要:

斜视的眼外肌药物注射疗法相比于斜视矫正手术具有更加安全、微创、麻醉时间短、术后疼痛轻、患者易于接受等优点。目前应用最广泛的减弱眼外肌力量的药物为肉毒毒素,其对小角度斜视、鼻内窥镜术后斜视、斜视矫正手术的辅助治疗等有重要作用;有效地增强肌肉力量的药物为布比卡因,其对小角度的共同性斜视、非陈旧性麻痹性斜视早期有治疗作用;肉毒素及布比卡因联合注射可对中等角度的水平共同性斜视、非陈旧性麻痹性斜视早期有较好治疗效果。(国际眼科纵览, 2018,  42:   169-174)

Abstract:

Compared to strabismus surgery, extra ocular muscle injection is a safer, more acceptable and less invasive way of treatment, which requires less anesthesia time and results in less pain. Nowadays, botulinum toxin has the most extensive clinical use for reducing muscle strength, especially in cases of small-angle strabismus, post squint surgery care, strabismus after nasal endoscopic surgery. Bupivacaine is able to strengthen muscle,providing treatment for small-angle concomitant strabismus and early paralytic strabismus. Combination injection of bupivacaine and botulinum toxin can be used to treat medium horizontal concomitant strabismus and early-onset paralytic strabismus.(Int Rev Ophthalmol, 2018, 42:  169-174)