国际眼科纵览 ›› 2025, Vol. 49 ›› Issue (3): 161-170.doi: 10. 3760/cma.j.cn115500-20250331-25301

• 综述 •    下一篇

眼力医学

何媛1 杜环1 葛萍1 贾渊博2,3 徐峰4 孙兴怀5   

  1. 1西安医学院第二附属医院眼科,西安 710038;2西安交通大学第二附属医院移植外科,西安 710004;3西安交通大学外科危重病急救与生命支持教育部重点实验室,西安 710049;4 西安交通大学生命科学与技术学院 生物医学工程教育部重点实验室 仿生工程与生物力学研究所,西安 710049;5复旦大学附属眼耳鼻喉科医院眼科,上海 200031

  • 收稿日期:2025-03-31 出版日期:2025-06-22 发布日期:2025-06-12
  • 通讯作者: 孙兴怀,Email: xhsun@shmu.edu.cn;徐峰,Email: fengxu@mail.xjtu.edu.cn
  • 基金资助:
    国家自然科学基金(12225208,82070964);陕西省杰出青年基金(2022JC-60);陕西省科技厅国际科技合作项目(2024GH-YBXM-20);眼病防治全国重点实验室专项经费(83000-32030002)

Oculomechanics medicine

He Yuan1, Du Huan1, Ge Ping1, Jia Yuanbo2,3, Xu Feng4, Sun Xinghuai5   

  1. 1Department of Ophthalmology,The Second Affiliated Hospital of Xi'an Medical University, Xi'an 710038, China; 2Department of Hepatobiliary Surgery and Liver Transplantation, The Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an 710004, China; 3China Key Laboratory of Surgical Critical Care and Life Support (Xi'an Jiaotong University), Ministry of Education, Xi’an 710049, China; 4MOE Key Laboratory of Biomedical Information Engineering, Bioinspired Engineering and Biomechanics Center, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an 710049, China; 5Eye & ENT Hospital of Fudan University, Shanghai 200031, China

  • Received:2025-03-31 Online:2025-06-22 Published:2025-06-12
  • Contact: Sun Xinghuai, Email: xhsun@shmu.edu.cn; Xu Feng, Email: fengxu@mail.xjtu.edu.cn
  • Supported by:
    National Natural Science Foundation of China (12225208, 82070964); Outstanding Youth Fund of Shaanxi Province (2022JC-60); International Scientific and Technological Cooperation Projects of Shaanxi Science and Technology Department(2024GH-YBXM-20); Dedicated Funding for the National Key Laboratory for the Prevention and Treatment of Eye Diseases(83000-32030002)

摘要: 随着医工交叉学科的发展,力学因素在眼病的发生发展以及诊疗过程中的作用日益凸显,成为基础与临床研究的热点。眼力医学聚焦于力学因素在眼病发生发展机制及诊断治疗的应用,以建立眼部组织力学参数与疾病诊疗的直接关联为核心,有机融合了眼生物力学、眼力生物学、眼力诊断学和眼力治疗学四个部分。其中,眼生物力学探究眼部组织生物学变化从而导致的力学响应;而眼力生物学是研究力学因素导致眼部组织的生物学变化;眼力诊断学依托力学特征研发新型诊断工具,提升眼部疾病早期诊断的精准度;眼力治疗学则基于眼部组织力学干预原理制定个性化治疗策略。


关键词: 眼生物力学, 眼力生物学, 眼力诊断学, 眼力治疗学

Abstract: With the development of interdisciplinary integration between medicine and engineering, the role of mechanical factors in the pathogenesis, progression, diagnosis, and treatment of ophthalmic diseases has become increasingly prominent, emerging as a focal point in both basic and clinical research.Oculomechanics medicine focuses on the application of mechanical factors in understanding disease mechanisms and developing therapeutic interventions in ophthalmology. Centered on establishing direct correlations between biomechanical parameters of ocular tissues and clinical management, this field organically integrates four key components: ocular biomechanics, ocular mechanobiology, ocular mechanodiagnostics, and ocular mechanotherapeutics. Specifically, ocular biomechanics investigates the mechanical responses arising from biological changes in ocular tissues, while ocular mechanobiology explores biological alterations induced by mechanical forces. Ocular mechanodiagnostics leverages mechanical characteristics to develop novel diagnostic tools for enhanced precision in early disease detection, whereas ocular mechanotherapeutics focuses on formulating personalized treatment strategies through mechanical interventions in ocular tissues.


Key words: Ocular biomechanics, Ocular mechanobiology, Ocular mechanodiagnostics, Ocular mechanotherapy