国际眼科纵览 ›› 2025, Vol. 49 ›› Issue (3): 170-176.doi: 10. 3760/cma.j.cn115500-20241216-25302

• 综述 • 上一篇    下一篇

影响角膜生物力学的因素

龚裕为  秦宇  郑亚捷  杨浩铭  李蕾  肖若涵  梁刚   

  1. 云南大学附属医院屈光中心,昆明 650000
  • 收稿日期:2024-12-16 出版日期:2025-06-22 发布日期:2025-06-12
  • 通讯作者: 梁刚,Email:29801242@qq.com
  • 基金资助:
    昆医联合专项-重点项目(202301AY070001-017)

Factors influencing corneal biomechanics

Gong Yuwei, Qin Yu, Zheng Yajie, Yang Haoming, Li Lei, Xiao Ruohan, Liang Gang   

  1. Refractive Center, Affiliated Hospital of Yunnan University, Kunming 650000, China
  • Received:2024-12-16 Online:2025-06-22 Published:2025-06-12
  • Contact: Liang Gang, Email:29801242@qq.com
  • Supported by:
     Kunming Medical Joint Special Project-Key Project (202301AY070001-017)

摘要: 角膜生物力学是决定角膜形态稳定和光学功能的基础特性。影响角膜生物力学的有生理(年龄、眼压、屈光状态、体内激素水平等)、行为(戴角膜接触镜、局部药物、揉眼、吸烟等)、眼及全身疾病(圆锥角膜、青光眼、糖尿病、干眼病、角结膜炎、甲状腺相关眼病等)以及手术/外伤等因素。这些因素共同调控着角膜的硬度、变形能力及能量耗散等特性。


关键词: 角膜, 角膜生物力学, 影响因素

Abstract: Corneal biomechanics are fundamental properties that determine the morphological stability and optical function of the cornea. Factors affecting corneal biomechanics include physiological factors (e.g., age, intraocular pressure, refractive status, hormonal levels), behavioral factors (e.g., contact lens wear, use of eye drops, eye rubbing, smoking), ocular and systemic diseases (e.g., keratoconus, glaucoma, diabetes mellitus, dry eye disease, keratoconjunctivitis, thyroid-associated ophthalmopathy), as well as surgical interventions and trauma. These factors collectively regulate corneal properties such as stiffness, deformability, and energy dissipation.


Key words: Corneal, Corneal biomechanics, Influencing factors