国际眼科纵览 ›› 2026, Vol. 50 ›› Issue (1): 39-46.doi: 10.3760/cma.i.cn115500-20250925-26106

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视觉刺激与训练技术在视神经疾病功能康复中的应用

刘小天 邬一楠 徐晓萍   

  1. 宁波市眼科医院,浙江宁波 315010
  • 收稿日期:2025-09-25 出版日期:2026-02-22 发布日期:2026-02-22
  • 通讯作者: 刘小天,Email:523755781@qq.com
  • 基金资助:
    宁波市鄞州区农业与社会发展科技计划(2019AS0031)

Application of visual stimulation and training techniques in functional rehabilitation of optic nerve diseases

Liu Xiaotian, Wu Yinan, Xu Xiaoping   

  1. Ningbo Eye Hospital, Ningbo Zhejiang 315010, China
  • Received:2025-09-25 Online:2026-02-22 Published:2026-02-22
  • Contact: Liu Xiaotian. Email: 523755781@qq.com
  • Supported by:
    Ningbo Yinzhou District Science and Technology Program for Agriculture and Social Development (2019AS0031)

摘要: 视神经疾病是导致不可逆性视力丧失的主要原因之一,传统治疗方法主要集中在病因控制而非功能恢复。近年来,基于神经可塑性理论的视觉训练与刺激技术为视神经疾病康复带来了新的希望。角膜电刺激在Leber遗传性视神经病变和青光眼等疾病中显示出良好应用前景;重复性经眶交流电刺激用个体化电极定位技术,能显著改善患者的视野和视力;40 Hz光闪烁刺激通过激活小胶质细胞促进视神经再生;虚拟现实视觉训练在青光眼患者中显示持续的视功能改善;皮层视觉假体技术在人体中首次实现字母识别功能。这些技术通过激活神经可塑性、促进神经保护和再生、改善视觉功能,为视神经疾病患者提供了新的治疗选择。随着技术不断发展完善,预见性康复干预策略的引入进一步优化了治疗效果,有望为更多患者带来康复希望。

关键词: 视神经疾病, 视觉训练, 电刺激, 神经可塑性, 康复治疗

Abstract: Optic nerve diseases are among the leading causes of irreversible vision loss, with traditional treatments primarily focusing on etiology control rather than functional recovery. In recent years, visual training and stimulation techniques based on neuroplasticity theory have brought new hope for optic nerve disease rehabilitation. Transcorneal electrical stimulation (TcES) shows promising applications in Leber hereditary optic neuropathy and glaucoma; repetitive transorbital alternating current stimulation (rtACS) with individualized electrode positioning technology can significantly improve patient's visual field and visual acuity; 40Hz light flicker stimulation promotes optic nerve regeneration by activating microglia; virtual reality visual training demonstrates sustained visual function improvement in glaucoma patients; cortical visual prosthesis technology achieves letter recognition function in humans for the first time. These techniques provide new treatment options for optic nerve disease patients by activating neuroplasticity, promoting neuroprotection and regeneration, and improving visual function. With continuous technological development and refinement, the introduction of predictive rehabilitation intervention strategies has further optimized treatment outcomes, offering hope for rehabilitation to more patients.

Key words: Optic nerve diseases, Visual training, Electrical stimulation, Neuroplasticity, Rehabilitation therapy