国际眼科纵览 ›› 2024, Vol. 48 ›› Issue (5): 378-384.doi: 10.3760/ cma.j.issn.1673-5803.2024.05.009

• 综述 • 上一篇    下一篇

眼部紫外线辐射伤及防护研究进展

崔名慧1,3陈纪良2于豪冰1刘小宇1宁哲1胡波1   

  1. 1海军特色医学中心,上海 200433;2海军军医大学基础医学院,上海 200433;3江苏海洋大学,江苏 连云港 222005
  • 收稿日期:2024-10-02 出版日期:2024-10-22 发布日期:2024-10-15
  • 通讯作者: 胡波,Email:hb8601@163.com

Research progress on eye ultraviolet radiation injury and protection

Cui Minghui1,3, Chen Jiliang2, Yu Haobing1, Liu Xiaoyu1, Ning Zhe1, Hu Bo1   

  1. 1 Naval Medical Center of PLA, Naval Medical University, Shanghai 200433, China; 2 College of Basic Medical Sciences, Naval Medical University, Shanghai 200433, China; 3 Jiangsu Ocean University, Lianyungang Jiangsu, 222005
  • Received:2024-10-02 Online:2024-10-22 Published:2024-10-15
  • Contact: Hu Bo, Email: hb8601@163.com

摘要: 近年来臭氧层的破坏导致中波紫外线(ultraviolet-B,UV-B)辐射增强,特别是在高原、海洋和极地等地区,由于UV-B反射率极高,电焊工、紫外线消毒工等特殊职业人群面临更高的紫外线眼病风险。UV-B辐射对眼部健康的潜在影响包括导致角膜炎、结膜炎、白内障、翼状胬肉和黄斑病变等眼部疾病。在物理防护方面,可使用符合UV400标准的防护眼镜,在临床治疗方面可选择抗炎、抗感染、表面麻醉和促进伤口愈合的药物等。此外,黄酮类、皂苷类、多肽类和酚类化合物等天然活性物质对UV-B辐射具有很好的防护作用,也可成为相关药物研发的潜在候选物质。(国际眼科纵览,2024, 48:378-384)

关键词: 中波紫外线, 紫外线眼疾, 天然产物

Abstract: In recent years, the destruction of the ozone layer has led to the enhancement of ultraviolet-B (UV-B) radiation, especially in plateaus, oceans and polar regions, due to the extremely high reflectivity of UV-B, which makes special occupational groups such as welders and ultraviolet disinfection workers face a higher risk of ultraviolet eye disease. To reduce the occurrence of eye diseases, physical protection can include using protective eyewear that meets the UV400 standard. In clinical treatment, options may include anti-inflammatory, anti-infection, surface anesthesia, and wound healing-promoting medications. In addition, natural active substances such as flavonoids, saponins, peptides and phenolic compounds have a good protection effect against UV-B radiation and can also be potential candidates for the research and development of related drugs.(Int Rev Ophthalmol, 2024, 48: 378-384)

Key words: UVB light, ultraviolet eye disease, natural products