关键词: 视网膜母细胞瘤, 介入治疗, 动脉内化疗

Abstract: Retinoblastoma (RB), a common malignant tumor of the eye in children, has been continuously evolving in its treatment methods as medical technology advances and greater attention is paid to patients' quality of life. In recent years, intra-arterial chemotherapy (IAC) has become an important treatment modality for RB, achieving targeted local chemotherapy of the tumor through ophthalmic artery drug delivery, significantly improving treatment outcomes and reducing systemic adverse reactions. This article provides a comprehensive review of the technical operation, chemotherapeutic drugs (melphalan, carboplatin, topotecan), eye and systemic adverse reactions, prognosis, and limitations of IAC in the treatment of RB, aiming to provide reference value for the improvement and development of IAC in clinical practice. (Int Rev Ophthalmol, 2024, 48:  476-480)

Key words: retinoblastoma; , interventional therapy； intra-arterial chemotherapy