Abstract: The traditional long pulse singlespot laser panretinal photocoagulation often is followed by some side effects in the treatment of diabetic retinopathy, including decreasing visual acuity, visual field constriction, aggravating macular edema,etc. Multispot laser, belongs to low intensity laser photocoagulation, is a focus of attention recently because of a short pulse, adjustable preset mode and other advantages, is a new treatment for diabetic retinopathy. Less research and application at home. The development status, the methods of multispot laser treatment of diabetic retinopathy, and its advantages and disadvantages are reviewed. The advantages of multispot laser are the smaller damage range, lighter pains, lower macular edema rate, less timeconsuming, and beautiful spot layout, but there are still some shortcomings.