国际眼科纵览

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黄斑色素光学密度测定的临床应用

张晨   陈伟   

  1. 310053 浙江中医药大学(张晨); 312000 浙江, 绍兴市人民医院 浙江大学绍兴医院眼科(陈伟)
  • 收稿日期:2015-05-24 出版日期:2015-10-22 发布日期:2015-10-27
  • 通讯作者: 陈伟 E-mail:chennweii@hotmail.com

The clinical application of macular pigment optical density measurement

ZHANG Chen1, CHEN Wei2.   

  1. 1. Zhejiang Chinese Medical University; 2. Department of Ophthalmology, Shaoxing People’s Hospital, Shaoxing Hospital Affiliated to Zhejiang University, 312000 Shaoxing, China
  • Received:2015-05-24 Online:2015-10-22 Published:2015-10-27
  • Contact: CHEN Wei E-mail:chennweii@hotmail.com

摘要:

眼底黄斑区具有独特的组织细胞结构,并具备最敏锐的视觉、色觉及形觉功能。人类黄斑色素的研究及其在眼底的分布目前可以通过测定黄斑色素光学密度(macular pigment optical density,MPOD)进行。以往的研究显示MPOD的下降与糖尿病及年龄相关性黄斑变性等疾病的发展有关,目前越来越多的研究表明,MPOD测定在临床上还可用于判断多种其他眼部及相关全身疾病(如青光眼、Stargardt病、2型黄斑毛细血管扩张症、Sj.gren-Larsson综合征等)的预后。(国际眼科纵览,2015,39:322.326)

Abstract:

The macular area, a unique tissue structure, has the most keen vision, color vision and perception in shape. The study of human macular pigment and its distribution in vivo is now possible through determination of macular pigment optical density (MPOD). Previous studies have shown that MPOD decreasing is related to the development of diabetes and age-related macular degeneration. Now, more and more studies show that MPOD measurement  can also be used to evaluate the prognosis of some eye diseases and related systemic diseases such as glaucoma, Stargardt disease, macular telangiectasia type 2 and Sjgren-Larsson syndrome.(Int Rev Ophthalmol,2015,39:322.326)