国际眼科纵览 ›› 2020, Vol. 44 ›› Issue (6): 397-401.doi: 10.3760/cma.j.issn/1673-5803.2020.06.005

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自身免疫病相关性角膜炎的研究进展

迪力努尔·吐逊江  丁琳   

  1. 新疆医科大学,乌鲁木齐 830054
  • 收稿日期:2020-05-06 出版日期:2020-12-22 发布日期:2020-12-29
  • 通讯作者: 丁琳,Email: dinglin85600@163.com

Research progress of autoimmune disease-related keratitis

Dilinuer·Tuxunjiang,Ding Lin    

  1. Xinjiang Medical University, Urumqi 830054, China
  • Received:2020-05-06 Online:2020-12-22 Published:2020-12-29
  • Contact: Ding Lin, Email:dinglin85600@163.com

摘要: 自身免疫病(autoimmune disease,AID)相关性角膜炎是以角膜炎症、角膜新生血管为主要特征,无活动性角膜感染表现。AID相关性角膜炎进展迅速,治疗难度大。其病因复杂多样,常见于类风湿性关节炎、系统性红斑狼疮、肉芽肿合并多发性脉管炎、Cogan综合征、冷卟啉相关周期性综合征、干燥综合征等。AID相关性角膜炎多与遗传因素、某些病毒的感染和自身免疫调节功能异常相关,但其具体发病机制尚不明确。(国际眼科纵览,2020, 44: 397-401)


关键词: 角膜炎, 自身免疫性疾病

Abstract: Autoimmune disease (AID) related keratitis is characterized by keratitis and corneal neovascularization, and has no active corneal infection. AID related keratitis develops rapidly and is difficult to treat. The etiology is complex and diverse. The common diseases are rheumatoid arthritis, systemic lupus erythematosus, granulomatosis with polyangiitis, Cogan syndrome, cryopirin-associated periodic syndrome, Sjgren's syndrome, etc. At present,  AID are mostly related to genetic factors, infection of some viruses and abnormal autoimmune regulation function in the literature reports, but the specific pathogenesis is still unclear. (Int Rev Ophthalmol, 2020, 44: 397-401)


Key words: keratitis, autoimmune disease