国际眼科纵览 ›› 2021, Vol. 45 ›› Issue (2): 81-88.doi: 10.3760/cma.j.issn.1673-5803.2021.02.001

• 综述 •    下一篇

非动脉炎性前部缺血性视神经病变治疗进展

王玲  杨晖   

  1. 中山大学中山眼科中心 眼科学国家重点实验室,广州 510060

  • 收稿日期:2020-05-14 出版日期:2021-04-22 发布日期:2021-04-28
  • 通讯作者: 通信作者:杨晖, Email:yanghui9@ hotmail.com
  • 基金资助:
    国家自然科学基金(81870656) 

Treatment of non-arteritic anterior ischemic optic neuropathy

Wang Ling, Yang Hui   

  1. State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou 510060, China
  • Received:2020-05-14 Online:2021-04-22 Published:2021-04-28
  • Contact: Yang Hui, Email: yanghui9@hotmail.com
  • Supported by:
    National Natural Science Foundation of China (81870656) 

摘要: 非动脉炎性前部缺血性视神经病变(nonarteritic anterior ischemic optic neuropathy,NAION)是全身血管危险因素及局部解剖因素等多因素共同参与的、发病机制复杂的视神经缺血性疾病。控制全身危险因素是治疗关键。目前三大治疗尝试包括改善循环(如眼压干预、体外反搏、手术),减轻视盘水肿(如全身或局部糖皮质激素、玻璃体注射抗新生血管药物),神经营养(如干细胞治疗等)。(国际眼科纵览,2021, 45: 81-88)


关键词: 非动脉炎性前部缺血性视神经病变, 视神经病变/治疗, 视神经病变/预防 

Abstract: Nonarteritic anterior ischemic optic neuropathy (NAION) is one of optic neuropathy with complex pathogenesis, which involves systemic vascular risk factors and regional anatomical factors. Control of systemic risk factors is the key to treatment. At present, the three major treatment attempts include improving circulation (such as intraocular pressure intervention, extracorporeal counterpulsation and surgery), reducing optic disc edema (such as systemic or local corticosteroid, local intravitreal injection of anti neovascularization drugs), and neurotrophic agents (such as stem cells therapy).(Int Rev Ophthalmol, 2021, 45: 81-88)


Key words: nonarteritic anterior ischemic optic neuropathy, optic neuropathy/treatment, optic neuropathy/prevention