关键词: 妊娠期高血压疾病, 眼底病变

Abstract: Hypertensive disorder complicating pregnancy (HDCP) is a common serious complication in obstetrics. Systemic small vessel spasm, vessel endothelial injury and ischemia are the basic pathophysiological changes, which in turn cause retinal ischemia, hypoxia, increased vascular permeability, and HDCP fundus lesions (retinal edema, hemorrhage, and retinal detachment, etc.). HDCP fundus lesions are divided into arterial spasm stage, arteriosclerosis stage and retinopathy stage. In addition to the fundus photographs, OCT can detect changes in retinal thickness and other structure, such as multiple superficial retinal detachment, high-reflection bright spots on the outside of the retina, Elschnig spots, and the thickness changes of the choroid etc. Fundus lesions in HDCP patients and the influencing factors related to the severity of fundus lesions include blood pressure, serum albumin, proteinuria and uric acid. In HDCP patients with fundus lesions, the incidence of low birth weight infants (<2.5 kg) is increased, but its effect on retinopathy of prematurity remains inconclusive.(Int Rev Ophthalmol, 2022, 46:  351-355)

Key words: hypertensive disorder complicating pregnancy, fundus disease