International Review of Ophthalmology

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Common ocular surface light damage and its pathogenesis

Zhang Yifan1,  Song Hui1, Zhao Shujun2, Nan Li1   

  1. 1 Clinical College of Ophthalmology Tianjin Medical University, Tianjin Eye Hospital, Tianjin Key Lab. of Ophthalmology and Visual Science, Tianjin Eye Institute, Tianjin 300002, China; 2 Tianjin Medical University Institute of Endocrinology, Zhuxianyi Memorial Hospital of Tianjin Medical University, Tianjin 300134, China
  • Received:2019-09-21 Online:2020-06-22 Published:2020-06-22
  • Contact: Nan Li, Email: 13820773411@163.com
  • Supported by:
    Natural Scientific Foundation of Tianjin (18JCDJC36400)

Abstract: The ocular surface is exposed to external light for a long time, and various ocular surface light damage diseases are common in the clinic. Short-wave invisible light, mainly ultraviolet rays can cause diseases such as acute photochemical keratitis, pterygium, keratoconus, etc. The most common ocular surface damage caused by visible light represented by blue light is dry eye, which is closely related to the use of electronic lighting and video terminals. Light damage causes ocular edema, angiogenesis, and tissue hyperplasia of the ocular surface. The main mechanisms are related to inflammation, apoptosis, and oxidative stress. (Int Rev Ophthalmol, 2020, 44：196-201)