International Review of Ophthalmology

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Roles of Müller cell related cytokines  in  repairment after retinal photocoagulation

ZHENG Lei1,  WEN Jia-min1,  ZHANG Fu-yan2   

  1. Zhongshan Ophthalmic Center,  State Key Laboratory of Ophthalmology,  Sun Yat-sen University,  Guangzhou 510060,  China; 2. Institute of Medical Sciences of Guizhou Medical  University, Department of Ophthalmology,  the Affiliated Hospital of Guizhou Medical University,  Guiyang 550004,  China
  • Received:2015-01-30 Online:2015-08-22 Published:2015-09-07
  • Contact: ZHANG Fu-yan, Email: simmonqiu1996@163.com E-mail:simmonqiu1996@163.com

Abstract:

Retinal photocoagulation is considered to be an effective measure for treating  fundus diseases,  but it also easy to cause the injury of adjacent retinal tissue. Müller cells  play the protective effect by producing related cytokines (such as intermediate filament protein, cyclin, heat shock protain, and ciliary neurotrophic factor) after retinal injury,  and participate in the repairment of retinal spots and scar formation. It’s also closely linked to the loss of visual field and visual retention after retinal photocoagulation.