Abstract:

Ellipsoid zone is an important reflection layer on optical coherence tomography (OCT) in the outer retina. It is an important sign to determine whether the visual cells are alive or not. A variety of fundus diseases can lead to the damages of the outer retina, especially the damages of the ellipsoid zone. The diseases that showed reversible ellipsoid zone damge included multiple evanescent white dot syndrome and syphilitic chorioretinitis. The diseases leading to non\|reversible ellipsoid zone damge include acute zonal occult outer retinopathy, retinal light damage, Stargardt disease, serpiginous choroiditis, retinitis pigmentosa, cancer\|associated retinopathy, etc. These diseases cause irreversible vision loss. The prognosis of vision can be determined by the integrity of the ellipsoid zone.(Int Rev Ophthalmol, 2019, 43: 361-365)