Abstract: With the popularity and daily use of cosmetics in recent years, eye makeup is becoming a major threat to the micro\|environment of the ocular surface. Eye makeup products and application methods are various, including eye liner, eye shadow, mascara, cosmetic contact lenses etc., which may induce or aggravate ocular diseases such as palpebral dermatitis, blepharitis, conjunctivitis, keratitis, corneal foreign bodies, dry eye and meibomian gland dysfunction (MGD) by mechanical friction, chemical substance migration and dissolution, allergy, infection and preservative toxicity. etc. This article reviews the pathogenicity and pathogenesis caused by eye makeup on ocular surface system in order to attract the attention of cosmetic crowd and clinicians.

Key words: makeup, ocular surface, meibomian gland dysfunction, keratitis