Abstract: Uveal melanoma is the most common malignant tumor in eyes for adults, and episcleral plaque radiotherapy is the primary eye\|conserving choice for uveal melanoma. Episcleral plaque radiotherapy can effectively control tumor growth, but tumor regression after radiotherapy has obvious heterogeneity. Some studies have suggested that the rate of postoperative tumor regression could be used as a prognostic factor for episcleral plaque radiotherapy, the faster the rate of tumor regression, the worse the prognosis of uveal melanoma. Some scholars have found that initial tumor thickness, chromosome 3 status and GEP typing are closely related to the tumor regression rate of uveal melanoma after episcleral plaque radiotherapy.

Key words: uveal neoplasms, melanoma, radiotherapy