Abstract: Polypoid choroidal angiopathy (PCV) is a common fundus disease in Asian people. It presented as orange-red nodular lesions under ophthalmoscope, which can associate with serous or bloody retinal pigment epithelial detachment and subretinal hemorrhage. Indocyanine green angiography (ICGA) is still recognized as the gold standard for diagnosis, but the rise of new auxiliary examination technologies such as OCT and OCTA also provide us with new ideas for the diagnosis of PCV. OCT can clearly display the level of branching vascular network (BVN), and brings us great convenience for follow-up because of its non-invasive and convenience. Clinical diagnosis criteria have also been established according to the OCT features of PCV. With the deepening of understanding of the PCV, different treatment options have been proposed, including monotherapy (such as, thermal laser photocoagulation, intravitreal anti-vascular endothelial growth factor, photodynamic therapy and vitrectomy) and combination therapy. In order to standardize the diagnosis and treatment of PCV, clinical features, diagnosis and treatment progress of PCV were reviewed in this paper.(Int Rev Ophthalmol, 2021, 45: 103-110)

Key words: polypoidal choroidal vasculopathy/diagnosis, polypoidal choroidal vasculopathy/treatment