Abstract: A well-constructed transparent corneal incision during cataract surgery can effectively prevent or reduce postoperative endophthalmitis and other complications, and improve the visual quality of patients. Femtosecond laser can improve the stability and tightness of the incision by making multi-plane and multi-shape incisions with different positions, angles and lengths. Although the reproducibility and reproducibility of the incision morphology are better than those made by corneal knife, there are still differences with preoperative presets. The effect of femtosecond laser made corneal incision on intraoperative astigmatism, corneal endothelial cell apoptosis, Descemet's membrane detachment and wound remodeling still needs more clinical research evidence. How femtosecond laser can accurately identify and locate the incision in the cornea and the optimal parameters for making the incision are still the focus of future research. (Int Rev Ophthalmol, 2023, 47: 126-130)

Key words: femtosecond laser, clear corneal incision, cataract surgery