International Review of Ophthalmology ›› 2023, Vol. 47 ›› Issue (6): 488-493.doi: 10.3760/cma.j.issn.1673-5803.2023.06.002

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Research status of optic disc structure in peripapillary hyper-reflective ovoid mass-like structures 

Meng Jiaxin1,2, Liu Xia3, Zhao Ying4   

  1. 1 Graduate School of Dalian Medical University, Dalian Liaoning 116044, China; 2 Department of Ophthalmology, Qingdao Municipal Hospital, Qingdao Shandong 266011, China; 3 Department of Ophthalmology, Tianjin Xiqing Hospital, Tianjin 300380, China; 4  Eye Institute of Shandong First Medical University, Qingdao Eye Hospital of Shandong First Medical University; State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology; School of Ophthalmology, Shandong First Medical University, Qingdao Shandong 266017, China
  • Received:2023-07-01 Online:2023-12-22 Published:2023-12-22
  • Contact: Zhao Ying, Email: Zhaoyingc2000@126.com
  • Supported by:
    Shandong Medical and Health Science and Technology Development Program (2018WS364)

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Abstract: Peripapillary hyper-reflective ovoid mass-like structures (PHOMS) are a novel finding observed through enhanced-depth imaging optical coherence tomography (EDI-OCT), appearing as annular or partially annular complexes containing vascular structures surrounding the optic disc on EDI-OCT images. PHOMS frequently coexist with tilted optic disc, optic disc drusen, demyelinating optic neuritis, Leber hereditary optic neuropathy, ischemic optic neuropathy, idiopathic intracranial hypertension, pseudopapilledema and other diseases related to axoplasmic flow stasis. However their pathophysiology and significance remain unclear. (Int Rev Ophthalmol, 2023, 47:  488-493)

Key words: peripapillary hyper-reflective ovoid mass-like structures, optic disc drusen, enhanced-depth imaging optical coherence tomography, tilted optic disc, demyelinating optic neuritis