Abstract: Among the large number of cases associated with novel coronavirus (SARS-CoV-2) infection, some cases involving structural lesions of the posterior segment of the eye have also been observed in addition to the more commonly reported ocular surface infections such as conjunctiva and cornea. As the virus continues to wreak havoc worldwide, the number of SARS-CoV-2 infected patients with posterior segment lesions of the eye is gradually increasing, and the main manifestations of SARS-CoV-2 posterior segment infection observed so far are fundus ischaemia and haemorrhage. The virus enters the cells through direct infection, vasculogenic or neurogenic infection and causes damage to the patients' vision through effects such as inflammatory responses and fundus vascular thrombosis. It is suggested that the value of fundus examination in assessing the severity of systemic lesions and the importance of timely fundus examination in COVID-19 patients for the prognosis of the disease and the assessment of long-term complications should be cherished. (Int Rev Ophthalmol, 2022, 46:  167-172)

Key words: COVID-19, SARS-CoV-2, eye infection