Abstract: Scleral contact lens (SCL) is a large-diameter, rigid, breathable contact lens. It is not contact with the cornea and is completely supported by the sclera. In recent years, SCL can form a tear reservoir between the posterior surface of the lens and the anterior surface of the cornea, neutralize optical aberrations to provide clear and stable vision for patients with corneal irregularities, due to the continuous improvement of its safety in clinical application, SCL has become a widely accepted new treatment method and can also effectively treat a variety of ocular surface diseases. In order to make the wearing of the lenses more convenient and comfortable, the SCL has been continuously updated in material and design, resulting in the emergence of mini SCL, which not only retain the advantages of SCL, have better application advantages in clinical applications, but also are easier to wear and have a wider range of applications. Mini-SCL can be used to treat primary or secondary irregular corneas, also can effectively treat dry eye caused by a variety of ocular surface diseases. In addition, Mini-SCL can also be combined with drugs to increase the efficacy of the drug. This article briefly describes the application, adverse reactions and related research progress of mini-SCL in ocular surface diseases, in order to provide reference for clinical treatment. (Int Rev Ophthalmol, 2024, 48: 20-24)

Key words: mini-scleral contact lenses, irregular cornea, dry eye ,  ,