关键词: 眼睑, 恶性肿瘤, 控制性切除

Abstract:

Objective To study the prognostic effects of surgical margin control for the eyelid malignancies. Design Retrospective case series study. Participants Sixty-eight patients’ clinical data who were diagnosed eyelid malignant tumors in Henan Eye Hospital from January 2011 to December 2015. Methods The patients’ recurrences and prognosis were studied and the effects of surgical margin control for the eyelid malignancies were analyzed. Main Outcome Measures TNM staging, size and the operation of the tumor, histopathologic type and patients’ recurrences and prognosis. Results The eyelid malignant tumor contained basal cell carcinoma (39 eyes,  57.3%)、 sebaceous gland carcinoma (28 eyes, 41.2%) and squamous cell carcinoma (1 eyes, 1.5%). At the end of followed-up, five cases were recurrence after operation and the recurrence rate is 7.4%. The recurrence rate of basal cell carcinoma is 2.6% (1/39) and the recurrence rate of sebaceous gland carcinoma is 14.3% (4/28). There were 63 patients who were followed without relapse, in which 20 cases (20/63, 31.7%) who were examined tumor cells remaining in the distal edge of the tissue by the surgical margin control achieved with paraffin-section, then the secondary surgery was performed until no tumor cells were found and the tissue defect repairing. Conclusion The surgical margin control for the eyelid malignancies can reduce the recurrence rate effectively. The normal tissue of the eyelid preserved as far as possible is useful for soft tissue defect repairing.

Key words: eyelid, malignant tumors, surgical margin control