关键词: 光学生物测量仪, 频域法, 扫频光源系统

Abstract:

Objective  To Compare ocular biometric measurements between a new swept-source optical coherence tomography OA-2000 and IOLmaster, and evaluate the detection rate, correlation and agreement. Design Diagnostic trial. Participants A sample of 83 eyes were selected from Department of Ophthalmology Beijing Hospital during December 2017. Methods The same eye of the same patient was measured by OA-2000 and IOLMaster respectively. Axial length (AL), keratometry (K) and anterior chamber depth (ACD) were compared and draw the correlation curve and bland-altman plot to evaluate the correlation and consistency of the two methods. Main Outcome Measures The detection rate, correlative coefficient, mean difference. Results The detection rate of OA-2000 and IOLmaster on AL was 97.6%, 75.3%, respectively. The detection rate of OA-2000 and IOLmaster on keratometry was 94.0%, 97.6%, respectively. The detection rate of OA-2000 and IOLmaster on ACD was 95.2%, 96.4%, respectively. The correlation coefficient of AL between OA-2000 and IOLmaster is almost 0.99, 0.97 or more of keratometry, and 0.88 of ACD. Bland-Altman plot showed the mean difference of both methods on AL is only 0.01mm, which is very close to the mean line. The mean difference of keratometry and ACD are more or less the mean line, but all of them are within the 95%CI. Conclusions The detection rate of new optical biometric OA-2000 on AL is significant better than IOLMaster. And the new method shows great advantage in opacity of refractive media. However, the result of corneal refraction and ACD is a little difference, which needs larger samples to observe. (Ophthalmol CHN, 2018, 27: 296-300)

Key words: optical biometer, frequency domain method, swept-source system